Cause
The cause of
chronic kidney disease isn't always known. But any
condition or disease that damages blood vessels or other structures in the
kidneys can lead to kidney disease. The most common causes of chronic kidney
disease are:
- .
It causes about 35% of all chronic kidney disease. High blood sugar
levels caused by diabetes damage blood vessels in the kidneys. If the blood
sugar level remains high, this damage gradually reduces the function of the
kidneys.
- (hypertension). It causes another 30% of all
kidney disease. Because blood pressure often rises with chronic kidney disease,
high blood pressure may further damage kidney function even when another
medical condition initially caused the disease.
Other conditions that can damage the kidneys and cause
chronic kidney disease include:
- Kidney diseases and infections, such as
, pyelonephritis,
, or a kidney problem you were born
with.
- Having a narrowed or blocked renal artery. The renal
artery carries blood to the kidneys.
- Long-term use of
. Examples
include
, such as
ibuprofen (Advil) and celecoxib (Celebrex), and certain
.
Diabetes and high blood pressure are the most common causes
of chronic kidney disease that leads to
. Diabetes or high blood pressure may
also speed up the progression of chronic kidney disease in someone who already
has the disease.