Examples

Thiazide diuretics

Loop diuretics

Potassium-sparing diuretics

Aldosterone receptor antagonists, such as spironolactone, are another type of potassium-sparing diuretic used for heart failure. For more information on this medicine, see Aldosterone Receptor Antagonists: Diuretics for Heart Failure.

How It Works

Diuretics stimulate the kidneys to remove more water and salt (sodium) from the body. This can help relieve swelling that happens because of heart failure.

Why It Is Used

These medicines are used if you have heart failure symptoms of fluid buildup (such as difficulty breathing or swelling in your legs and ankles). Diuretics are often used with ACE inhibitors and may be combined with other medicines.

Another type of diuretic called an aldosterone receptor antagonist may be an option for some people who have heart failure.

How Well It Works

Diuretics help rid the body of extra fluid and sodium. They can help relieve some symptoms of heart failure such as swelling in the legs.¹

Side Effects

All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.

Here are some important things to think about:

• Usually the benefits of the medicine are more important than any minor side effects.
• Side effects may go away after you take the medicine for a while.
• If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.

Call 911 or other emergency services right away if you have:

• Trouble breathing.
• Hives.
• Swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have symptoms of changes in potassium levels:

• Confusion
• Dry mouth or increased thirst
• Irregular heartbeat
• Muscle cramps or pain
• Numbness or tingling in your hands, feet, or lips

Other side effects of this medicine include:

• Loss of appetite.
• Stomach aches.
• Nausea.
• Sensitive skin to sunlight.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)