Thrombin

Alternate Terms:
  • Activated Factor II
  • Activated Factor IIa
  • Prothrombin
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Anemia, Blood Clots & Blood Disorders
Prothrombin Time



Thrombin Definition by Healthwise:

Thrombin

Thrombin is a substance (enzyme) in the bloodstream that is needed for blood to clot. When a person is cut or wounded, thrombin and a protein called fibrinogen make a stringy material that traps blood cells and then gradually decomposes as the area heals.

Only thrombin located at the area of the injury is activated, and only for a few seconds. This process helps prevent a potentially dangerous blood clot, called a thrombus, from forming and traveling through the bloodstream.

Author: Robin Parks, MS
Medical Review: E. Gregory Thompson, MD - Internal Medicine
Jeffrey J. Gilbertson, MD - Cardiovascular Surgery
Last Updated: January 15, 2008

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