Rheumatoid Factor

Alternate Terms:
  • RF
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Arthritis & Gout
Rheumatoid Factor (RF)



Rheumatoid Factor Definition by Healthwise:

Rheumatoid factor (RF)

Rheumatoid factor (RF) is a protein (antibody) made by the immune system that can attack the body's own tissues. An elevated rheumatoid factor may indicate the presence of an inflammatory disease.

Rheumatoid factor can be measured with a blood test. This is most helpful for diagnosing rheumatoid arthritis, lupus, and Sjögren's syndrome. Certain heart and liver diseases, infectious diseases (such as tuberculosis), and normal aging may also increase RF levels.

Author: Jeannette Curtis
Medical Review: Patrice Burgess, MD - Family Medicine
Adam Husney, MD - Family Medicine
Kathleen Romito, MD - Family Medicine
Last Updated: May 25, 2007

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