Overview of Headaches in Adults (Cleveland Clinic)

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Secondary headaches
Secondary headaches, or those that result from another medical condition, include sinus headaches, hormone headaches, chronic progressive headaches or headaches that occur as a result of a head injury, trauma, or more serious condition such as a tumor.

  • Sinus headaches: headaches associated with a deep and constant pain in the cheekbones, forehead, or bridge of the nose. The pain usually intensifies with sudden head movement or straining and usually occurs with other sinus symptoms, such as nasal discharge, feeling of fullness in the ears, fever, and facial swelling.
  • Hormone headaches: headaches in women are often associated with changing hormone levels that occur during menstruation, pregnancy, and menopause. Chemically induced hormone changes, such as with birth control pills, also trigger headaches in some women.
  • Chronic progressive headaches: headaches that get worse and happen more often over time. Chronic progressive headaches are also called traction or inflammatory headaches. These are the least common type of headache, accounting for less than 5% of all headaches. Chronic progressive headaches may be the result of an illness or disorder of the brain or skull.

Are headaches hereditary?
Yes, headaches, especially migraines, have a tendency to run in families. Children who have migraines usually have at least one parent who also suffers from the condition. Headaches also can be triggered by specific environmental factors that are shared in a family’s household, such as exposure to second-hand tobacco smoke, strong odors from household chemicals or perfumes, exposure to certain allergens, or eating certain foods. Stress, pollution, noise, lighting, and weather changes are other environmental factors that can trigger headaches for some people.

People with migraines may inherit abnormalities in certain areas of the brain, as well as the tendency to be affected by certain migraine triggers, such as fatigue, bright lights, weather changes, and others.

What causes headaches?
Headache pain results from signals interacting among the brain, blood vessels and surrounding nerves. During a headache, specific nerves of the blood vessels and head muscles are activated and send pain signals to the brain. It’s not clear, however, why these signals are activated in the first place.

There is a migraine "pain center" or generator in the mid-brain area. A migraine begins when hyperactive nerve cells send out impulses to the blood vessels, causing constriction, followed by the dilation of these vessels and the release of prostaglandins, serotonin and other inflammatory substances that cause the pulsation to be painful. Serotonin is a naturally occurring chemical essential for certain body processes.

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Last Updated: 2/1/2012

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