Corneal Conditions (Cleveland Clinic)

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Symptoms of keratitis include:

  • Severe pain
  • Reduced visual clarity
  • Corneal discharge

Treatment usually includes antibiotic or antifungal eye drops.

Ocular herpes (herpes of the eye)
This is a viral infection of the eye that may reoccur. The main cause of ocular herpes is the herpes simplex virus I (HSV I). This is the same virus that causes cold sores, but ocular herpes can also result from the sexually transmitted herpes simplex II virus (HSV II) that causes genital herpes.

Ocular herpes produces sores on the surface of the cornea; over time, the inflammation can spread deeper into the cornea and eye.

There is no cure for ocular herpes, but it can often be controlled with the use of antiviral drugs.

Herpes zoster (shingles)
Shingles is a recurrence of the chicken pox virus in people who have already had the disease. After the bout of chicken pox, this virus usually remains inactive within the nerves of the body. It can later travel down these nerves, infecting specific parts of the body, like the eye. Herpes zoster can cause blisters or lesions on the cornea, fever, and pain from nerve fibers. Corneal lesions usually heal by themselves, but antiviral treatment may reduce the inflammation.

Shingles is a recurrence of the chicken pox virus in people who have already had the disease. After the bout of chicken pox, this virus usually remains inactive within the nerves of the body. It can later travel down these nerves, infecting specific parts of the body, like the eye. Herpes zoster can cause blisters or lesions on the cornea, fever, and pain from nerve fibers. Corneal lesions usually heal by themselves, but antiviral treatment may reduce the inflammation.

Shingles can occur in anyone exposed to the chicken pox virus, but there is an increased risk in older adults (especially those over age 80) and people with a weakened immune system.

See your doctor if you have any symptoms of shingles.

Corneal dystrophies
There are more than 20 corneal dystrophies, diseases that cause structural problems with the cornea. Some of the most common are:

Keratoconus
Keratoconus is a progressive disease in which the cornea thins and changes shape. Keratoconus changes the curvature of the cornea, creating either mild or severe distortion, called astigmatism, and usually nearsightedness. Keratoconus may also cause swelling and scarring of the cornea and vision loss.

Causes of keratoconus include:

  • Genetics (a person can inherit a tendency to get the condition from a parent.)
  • Eye trauma (for example, from rubbing your eyes or long-term use of hard contacts)
  • Eye diseases, such as retinitis pigmentosa, retinopathy of prematurity, and vernal keratoconjunctivitis
  • Other diseases, like Down syndrome, osteogenesis imperfecta, Addison's disease, Leber's congenital amaurosis, and Ehlers-Danlos Syndrome

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Last Updated: 6/8/2010

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