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Voriconazole

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Generic:voriconazole (vor i KON a zole)
Brand:VFEND

What is voriconazole?
What is the most important information I should know about voriconazole?
What should I discuss with my healthcare provider before taking voriconazole?
How should I take voriconazole?
What happens if I miss a dose?
What happens if I overdose?
What should I avoid while taking voriconazole?
What are the possible side effects of voriconazole?
What other drugs will affect voriconazole?
Where can I get more information?


What is voriconazole?

Voriconazole is an antifungal medication.

Voriconazole is used to treat infections caused by yeast or other types of fungus.

Voriconazole may also be used for purposes not listed in this medication guide.

What is the most important information I should know about voriconazole?

Do not use voriconazole if you are pregnant. It could harm the unborn baby.

There are many other medicines that can cause serious or life-threatening drug interactions with voriconazole. Tell your doctor about all the prescription and over-the-counter medications you use.

Before taking voriconazole, tell your doctor if you have heart rhythm problems, an electrolyte imbalance, liver or kidney disease, or a history of allergy to other antifungal medications such as fluconazole (Diflucan), ketoconazole (Nizoral), or itraconazole (Sporanox).

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Voriconazole will not treat a viral infection such as the common cold or flu.

Voriconazole can cause problems with your vision. If you use this medicine for more than 28 days, you may need to have your eyes checked.

What should I discuss with my healthcare provider before taking voriconazole?

You should not take this medication if you are allergic to voriconazole, or if you are taking any of the following drugs:

  • carbamazepine (Carbatrol, Equetro, Tegretol);

  • cisapride (Propulsid);

  • pimozide (Orap);

  • quinidine (Quin-G);

  • sirolimus (Rapamune);

  • mephobarbital (Mebaral) or phenobarbital (Solfoton);

  • ritonavir (Norvir, Kaletra) in high doses;

  • rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane, Rifater);

  • St. John's wort; or

  • an ergot medicine such as ergotamine (Ergomar, Cafergot, Ercaf, Wigraine, others) or dihydroergotamine (D.H.E., Migranal).

The drugs listed above can cause dangerous serious or life-threatening drug interactions with voriconazole. Tell your doctor about all other medicines you are using.

To make sure you can safely take voriconazole, tell your doctor if you have any of these other conditions:

  • heart rhythm problems;

  • a metabolic disorder such as high or low levels of calcium, potassium, or magnesium;

  • liver disease;

  • kidney disease; or

  • a history of allergy to other antifungal medications such as fluconazole (Diflucan), ketoconazole (Nizoral), or itraconazole (Sporanox).

Voriconazole tablets contain lactose. Before taking a voriconazole tablet, tell your doctor if you have a hereditary form of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption.

FDA pregnancy category D. Do not use voriconazole if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known if voriconazole passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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Copyright © 2010 Lexi-Comp, Inc. and/or Cerner Multum, Inc. All rights reserved. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

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