What is trandolapril and verapamil?
Trandolapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.
Verapamil is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.
The combination of trandolapril and verapamil is used to treat high blood pressure (hypertension).
Trandolapril and verapamil may also be used for purposes not listed in this medication guide.
What is the most important information I should know about trandolapril and verapamil?
Do not use trandolapril and verapamil if you are pregnant. It could harm the unborn baby. Stop using this medication and tell your doctor right away if you become pregnant.
You should not use this medicine if you have certain serious heart problems, or if you are allergic to trandolapril (Mavik) or similar medicines such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), or ramipril (Altace).
There are many other drugs that can interact with trandolapril and verapamil. Tell your doctor about all medications you use.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.
What should I discuss with my healthcare provider before taking trandolapril and verapamil?
You should not use this medicine if you are allergic to trandolapril (Mavik) or verapamil (Calan, Covera, Isoptin, Verelan), or if you have:
certain serious heart conditions, especially "sick sinus syndrome" or "AV block" (unless you have a pacemaker);
a heart rhythm disorder;
low blood pressure; or
if you are allergic to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), or ramipril (Altace).
To make sure you can safely take trandolapril and verapamil, tell your doctor if you have any of these other conditions:
kidney disease (or if you are on dialysis);
liver disease;
congestive heart failure;
diabetes;
a nerve-muscle disease such as muscular dystrophy; or
a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.
FDA pregnancy category D. Do not use trandolapril and verapamil if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Trandolapril and verapamil can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking trandolapril and verapamil.
Trandolapril and verapamil can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using trandolapril and verapamil.