What is thiotepa?
Thiotepa is a cancer (antineoplastic) medication. Thiotepa interferes with the growth of cancer cells and slows their growth and spread in the body.
Thiotepa is used in the treatment of cancers of the breast, ovary, bladder, and others.
Thiotepa may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about thiotepa?
Thiotepa should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.
Serious side effects have been reported with the use of thiotepa including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); severe heart damage with prolonged use; decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection); severe nausea, vomiting, diarrhea, and loss of appetite; and others. Talk to your doctor about the possible side effects from treatment with thiotepa.
What should I discuss with my healthcare provider before using thiotepa?
Do not use thiotepa without first talking to your doctor if you have
The use of thiotepa may be dangerous if you have any of the conditions listed above.
Thiotepa is in the FDA pregnancy category D. This means that thiotepa is known to be harmful to an unborn baby. Do not use thiotepa without first talking to your doctor if you are pregnant. Discuss with your doctor the appropriate use of birth control during treatment with thiotepa if either you or your partner is of childbearing potential.
It is not known whether thiotepa passes into breast milk. Do not take thiotepa without first talking to your doctor if you are breast-feeding a baby.
The safety and effectiveness of thiotepa in children has not been established.