Cholestyramine helps reduce cholesterol (fatty acids) in the blood. High cholesterol is associated with an increased risk of heart disease and atherosclerosis (clogged arteries).

Cholestyramine is used to lower high levels of cholesterol in the blood, especially low-density lipoprotein (LDL) ("bad" cholesterol).

Cholestyramine powder is also used to treat itching caused by a blockage in the bile ducts of the gallbladder.

Cholestyramine may also be used for purposes not listed in this medication guide.

You should not take this medication if you are allergic to cholestyramine, or if you have a blockage in your stomach or intestines.

Before taking cholestyramine, tell your doctor if you have a thyroid disorder, diabetes, kidney or liver disease, or chronic constipation.

Avoid taking other medications at the same time you take cholestyramine. Wait at least 4 to 6 hours after taking cholestyramine before you take any other medications.

You should not take this medication if you are allergic to cholestyramine, or if you have a blockage in your stomach or intestines.

To make sure you can safely take cholestyramine, tell your doctor if you have any of these other conditions:

• a thyroid disorder;

• diabetes,

• kidney disease,

• liver disease, or

• chronic constipation.

FDA pregnancy category C. It is not known whether cholestyramine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Taking cholestyramine can make it harder for your body to absorb certain vitamins your body needs while you are nursing a baby. Do not take cholestyramine without telling your doctor if you are breast-feeding.

This medicine may contain phenylalanine. Talk to your doctor before using cholestyramine if you have phenylketonuria (PKU).