Nepafenac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It reduces pain and inflammation in the eyes.

Nepafenac ophthalmic (for the eyes) is used to reduce pain and swelling after cataract surgery.

Nepafenac ophthalmic may also be used for other purposes not listed in this medication guide.

Before using nepafenac ophthalmic, tell your doctor if you are allergic to any drugs or other eye drops

Also tell your doctor if you have diabetes, dry eye syndrome, rheumatoid arthritis, a bleeding or blood-clotting disorder, such as hemophilia, or arthritis.

Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using nepafenac before putting your contact lenses in.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use nepafenac ophthalmic for longer than 14 days after your surgery unless your doctor tells you to.

You should not use this medication if you are allergic to nepafenac.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

• diabetes;

• dry eye syndrome;

• rheumatoid arthritis;

• a bleeding or blood-clotting disorder, such as hemophilia; or

• arthritis.

Do not use nepafenac ophthalmic while wearing contact lenses. If you wear contact lenses take them out or talk to your doctor before using the medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby, especially if during the last part of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether nepafenac ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.