Nafarelin nasal is a man-made form of a protein that is like a hormone in the body that helps regulate the menstrual cycle, fertility, and sexual development during puberty.

Nafarelin nasal is used to treat precocious puberty in both male and female children. It is also used to treat endometriosis in women who are 18 years of age or older.

Nafarelin nasal may also be used for purposes not listed in this medication guide.

Nafarelin nasal can harm an unborn baby or cause birth defects. Do not use nafarelin nasal if you are pregnant.

You should not use this medication if you are allergic to nafarelin or similar medicines such as leuprolide (Lupron, Eligard, Viadur), goserelin (Zoladex), histrelin (Vantas), or triptorelin (Trelstar).

If you are a woman, you should not use nafarelin nasal if you have abnormal vaginal bleeding that has not been checked by a doctor; or if you are pregnant or breast-feeding.

Before using nafarelin nasal, tell your doctor if you have polycystic ovary disease, low bone mineral density, a history of osteoporosis, sneezing or a stuffy nose, diabetes, heart disease, high blood pressure, recent weight gain, high cholesterol, if you take steroids or seizure medication, if you smoke, or if you drink large amounts of alcohol.

Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Call your doctor at once if you have heavy or continued menstrual bleeding, pelvic pain or swelling, increased thirst, increased urination, chest pain or heavy feeling, pain spreading to the arm or shoulder, sweating or general ill feeling, sudden numbness or weakness, sudden severe headache, confusion, or problems with vision, speech, or balance.

You should not use this medication if you are allergic to nafarelin or similar medicines such as leuprolide (Lupron, Eligard, Viadur), goserelin (Zoladex), histrelin (Vantas), or triptorelin (Trelstar).

If you are a woman, you should not use nafarelin nasal if you have:

• abnormal vaginal bleeding that has not been checked by a doctor; or

• if you are pregnant or breast-feeding.

To make sure you can safely use nafarelin nasal, tell your doctor if you have any of these other conditions:

• diabetes, heart disease, high blood pressure, recent weight gain, high cholesterol (especially in men);

• polycystic ovary disease;

• low bone mineral density;

• a personal or family history of osteoporosis;

• sneezing or a runny nose;

• if you take steroids or seizure medication; or

• if you smoke or drink large amounts of alcohol.

FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use nafarelin nasal if you are pregnant. Tell your doctor right away if you become pregnant during treatment.

Use a barrier form of birth control (such as a condom or diaphragm with spermicide). Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment.

It is not known whether nafarelin nasal passes into breast milk or if it could harm a nursing baby. Do not breast-feed while using this medication.