Methsuximide is an anti-epileptic medication, also called an anticonvulsant.

Methsuximide is used alone or in combination with other medications to treat absence seizures (also called "petit mal" seizures) in adults and children.

Methsuximide may also be used for purposes not listed in this medication guide.

Methsuximide can cause a decrease in many types of blood cells (white cells, red cells, platelets). Call your doctor at once if you have any unusual bleeding, weakness, or any signs of infection, even if these symptoms first occur after you have been using the medication for several months.

Methsuximide may also cause liver damage. Call your doctor if you have symptoms such as loss of appetite, stomach pain, or jaundice (yellowing of the skin or eyes).

You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Do not stop using methsuximide without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using methsuximide suddenly. You may need to use less and less before you stop the medication completely.

Contact your doctor if your seizures get worse or you have them more often while taking methsuximide.

Wear a medical alert tag or carry an ID card stating that you take methsuximide. Any doctor, dentist, or emergency medical care provider who treats you should know that you take seizure medication.

You should not use this medication if you are allergic to methsuximide or to other seizure medications.

To make sure you can safely take methsuximide, tell your doctor if you have any of these other conditions:

• lupus;

• liver disease;

• kidney disease; or

• a history of depression, mental illness, or suicidal thoughts or actions.

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

It is not known whether methsuximide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Although methsuximide might harm an unborn baby, having a seizure during pregnancy could harm both mother and baby. If you become pregnant while taking methsuximide, do not stop taking it without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of methsuximide on the baby.

It is not known whether methsuximide passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.