Fenofibrate helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

Fenofibrate is used to treat high cholesterol and high triglyceride levels.

Fenofibrate may also be used for other purposes not listed in this medication guide.

Fenofibrate is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Avoid drinking alcohol while taking fenofibrate. Alcohol can raise triglyceride levels, and may also damage your liver while you are taking fenofibrate.

Fenofibrate has been associated with a rare but serious side effect of the muscles. Contact your doctor at once if you have unusual muscle pain, tenderness, or weakness especially if accompanied by fever or flu-like feeling.

You should not use fenofibrate if you have:

• hepatitis or cirrhosis of the liver;

• severe kidney disease; or

• gallbladder disease.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take this medication:

• liver disease;

• kidney disease;

• hypothyroidism (an underactive thyroid gland); or

• diabetes.

FDA pregnancy category C. It is not known whether fenofibrate is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Fenofibrate should not be used by nursing mothers. Do not take fenofibrate without telling your doctor if you are breast-feeding a baby.