What is pancrelipase?
Pancrelipase is a combination of three enzymes (proteins): lipase, protease, and amylase. These enzymes are normally produced by the pancreas and are important in the digestion of fats, proteins, and sugars.
Pancrelipase is used to replace these enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, including cystic fibrosis, chronic inflammation of the pancreas, or blockage of the pancreatic ducts.
Pancrelipase may also be used following surgical removal of the pancreas.
Pancrelipase may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about pancrelipase?
You should not take pancrelipase if you are allergic to pork proteins.
Before taking pancrelipase, tell your doctor if you have gout, kidney disease, a history of intestinal blockage, a sudden onset of pancreatitis, or worsening of chronic pancreatic disease.
Use pancrelipase regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Do not hold the tablets or capsule contents in your mouth. The medication may irritate the inside of your mouth.
Do not inhale the powder from a pancrelipase capsule, or allow it to touch your skin. It may cause irritation, especially to your nose and lungs.
If you miss a dose of this medicine, skip the missed dose and wait until your next scheduled dose to take the medicine. Do not take extra medicine to make up the missed dose.
What should I discuss with my healthcare provider before taking pancrelipase?
You should not take pancrelipase if you are allergic to pork proteins.
If you have any of these other conditions, you may need a pancrelipase dose adjustment or special tests:
kidney disease;
gout;
a history of blockage in your intestines;
a sudden onset of pancreatitis; or
worsening of chronic pancreatic disease.
This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether pancrelipase passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.