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Imatinib

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Generic:imatinib (im MA ta nib)
Brand:Gleevec

What is imatinib?
What is the most important information I should know about imatinib?
What should I discuss with my healthcare provider before taking imatinib?
How should I take imatinib?
What happens if I miss a dose?
What happens if I overdose?
What should I avoid while taking imatinib?
What are the possible side effects of imatinib?
What other drugs will affect imatinib?
Where can I get more information?


What is imatinib?

Imatinib interferes with the growth of some cancer cells.

Imatinib is used to treat a certain types of leukemia (blood cancer) such as Philadelphia chromosome positive chronic myeloid leukemia (CML). It is also used to treat certain tumors of the stomach and digestive system.

Imatinib may also be used for purposes not listed in this medication guide.

What is the most important information I should know about imatinib?

Do not use imatinib if you are pregnant. It could harm the unborn baby.

Before using this medication, tell your doctor if you have liver disease, kidney disease, underactive thyroid, congestive heart failure, a history of stomach ulcer or bleeding, or if you are receiving chemotherapy.

Take this medicine with a large glass of water.

Imatinib should be taken with a meal. Do not take the medicine on an empty stomach.

If you miss a dose, take the medicine as soon as you remember, making sure you also eat a meal and drink a large glass of water. Skip the missed dose if it is almost time for your next meal. Do not take extra medicine to make up the missed dose.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

What should I discuss with my healthcare provider before taking imatinib?

You should not use this medication if you are allergic to imatinib.

To make sure you can safely take imatinib, tell your doctor if you have any of these other conditions:

  • liver disease;

  • kidney disease;

  • underactive thyroid, recent or upcoming thyroid surgery;

  • heart disease, congestive heart failure;

  • history of stomach ulcer or bleeding; or

  • if you are receiving chemotherapy.

FDA pregnancy category D. Do not use imatinib if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether imatinib passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Imatinib can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Do not give this medication to anyone under 2 years old without medical advice.

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Copyright © 2010 Lexi-Comp, Inc. and/or Cerner Multum, Inc. All rights reserved. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

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