What is glipizide?
Glipizide is an oral diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin.
Glipizide is used together with diet and exercise to treat type 2 diabetes.
Glipizide may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about glipizide?
Do not use this medication if you are allergic to glipizide, or if you are in a state of diabetic ketoacidosis. Call your doctor for treatment with insulin.
Before taking glipizide, tell your doctor if you have kidney or liver disease, chronic diarrhea or a blockage in your intestines, glucose-6-phosphate dehydrogenase deficiency (G6PD), a disorder of your pituitary or adrenal glands, a history of heart disease, or if you are malnourished.
Take care not to let your blood sugar get too low. Low blood sugar (hypoglycemia) can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremors, irritability, or trouble concentrating. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency.
Also watch for signs of blood sugar that is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss. Your blood sugar will need to be checked often, and you may need to adjust your glipizide dose.
Glipizide is only part of a complete program of treatment that may also include diet, exercise, weight control, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.
What should I discuss with my doctor before taking glipizide?
Do not use this medication if you are allergic to glipizide, or if you are in a state of diabetic ketoacidosis. Call your doctor for treatment with insulin.
To make sure you can safely take glipizide, tell your doctor if you have any of these other conditions:
liver disease;
kidney disease;
chronic diarrhea or a blockage in your intestines;
an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);
a disorder of your pituitary or adrenal glands;
a history of heart disease; or
if you are malnourished.
Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with glipizide.
FDA pregnancy category C. It is not known whether glipizide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether glipizide passes into breast milk or if it could be harmful to a nursing baby. Do not take glipizide without telling your doctor if you are breast-feeding a baby.