Rasburicase helps keep uric acid levels in the body from getting too high. Uric acid levels can increase during cancer treatments when tumor cells break down.

Rasburicase is used to manage uric acid levels in adults and children receiving cancer treatment for leukemia, lymphoma, and certain tumors.

Rasburicase may also be used for other purposes not listed in this medication guide.

You should not receive rasburicase if you are allergic to it, or if you have an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

If you are of African or Mediterranean descent, you may need a rasburicase dose adjustment or special tests.

Tell your caregivers at once if you have a serious side effect such as a change in your mental state, dizziness or tired feeling, blue colored lips, feeling light-headed or short of breath, irregular heart rate, seizure, mouth sores, pale or yellowed skin, dark colored urine, fever, confusion, or weakness.

You should not receive this medication if you have ever had an allergic reaction or blood cell problems after receiving rasburicase, or if you have an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

If you are of African or Mediterranean descent, you may need a rasburicase dose adjustment or special tests:

FDA pregnancy category C. It is not known whether rasburicase will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication..

It is not known whether rasburicase passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.