Erythromycin is in a group of drugs called macrolide antibiotics. Erythromycin fights bacteria in the body.

Sulfisoxazole is a sulfa drug that also fights bacteria in the body.

The combination of erythromycin and sulfisoxazole is used to ear infections in children.

Erythromycin and sulfisoxazole may also be used for other purposes not listed in this medication guide.

Do not take this medication if you are allergic to erythromycin or sulfisoxazole, if you are in your 9th month of pregnancy, or if you are breast-feeding a baby younger than 2 months old.

Before taking erythromycin and sulfisoxazole, tell your doctor if you have liver or kidney disease, diabetes, myasthenia gravis, a history of "Long QT Syndrome," or if you are allergic to sulfa drugs or other antibiotics such as azithromycin (Zithromax) or clarithromycin (Biaxin).

Take this medication for the full prescribed length of time. Your symptoms may get better before the infection is completely cleared. Erythromycin and sulfisoxazole will not treat a viral infection such as the common cold or flu.

Do not take this medication if you are allergic to erythromycin or sulfisoxazole, or if::

• you are in your 9th month of pregnancy; or

• you are breast-feeding a baby younger than 2 months old.

Erythromycin may interact with these medicines and could cause dangerous or life-threatening heart rhythm disorders.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

• kidney disease;

• liver disease;

• diabetes;

• myasthenia gravis;

• a history of "Long QT Syndrome"; or

• if you are allergic to sulfa drugs or other antibiotics such as azithromycin (Zithromax) or clarithromycin (Biaxin).

FDA pregnancy category C. It is not known whether erythromycin and sulfisoxazole is harmful to an unborn baby when taken in early pregnancy. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Do not take erythromycin and sulfisoxazole during late pregnancy.

Erythromycin and sulfisoxazole can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not take erythromycin and sulfisoxazole if you are breast-feeding a baby younger than 2 months old.

Older adults may be more likely to have side effects from this medication.

Do not give this medication to a child younger than 2 months old.