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Emend for Injection

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Generic:fosaprepitant (FOS a PREP i tan t)
Brand:Emend for Injection

What is fosaprepitant?
What is the most important information I should know about fosaprepitant?
What should I discuss with my health care provider before I receive fosaprepitant?
How is fosaprepitant given?
What happens if I miss a dose?
What happens if I overdose?
What should I avoid while receiving fosaprepitant?
What are the possible side effects of fosaprepitant?
What other drugs will affect fosaprepitant?
Where can I get more information?


What is fosaprepitant?

Fosaprepitant blocks the actions of chemicals in the body that trigger nausea and vomiting.

Fosaprepitant is used together with other medications to prevent nausea and vomiting that may be caused by cancer chemotherapy.

Fosaprepitant is given ahead of time and will not treat nausea or vomiting that you already have.

Fosaprepitant may also be used for purposes not listed in this medication guide.

What is the most important information I should know about fosaprepitant?

You should not receive fosaprepitant if you are taking cisapride (Propulsid) or pimozide (Orap). These drugs may cause life-threatening interactions when taken together with fosaprepitant.

Before you receive fosaprepitant, tell your doctor if you have liver disease. You may need a dose adjustment or special tests to safely use this medication.

Fosaprepitant can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication. Talk to your doctor about the use of a non-hormonal back-up form of birth control (such as condoms, a diaphragm, or spermicides) during treatment with fosaprepitant, and for 1 month afterward.

There are many other medicines that can interact with fosaprepitant. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What should I discuss with my health care provider before I receive fosaprepitant?

You should not use this medication if you are allergic to fosaprepitant, aprepitant (oral Emend).

The following drugs should not be used while you are receiving fosaprepitant:

  • cisapride (Propulsid); or

  • pimozide (Orap).

To make sure you can safely take fosaprepitant, tell your doctor if you have liver disease.

Fosaprepitant can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication. Talk to your doctor about the use of a non-hormonal back-up form of birth control (such as condoms, a diaphragm, or spermicides) during treatment with fosaprepitant and for at least 1 month after your treatment ends.

FDA pregnancy category B. Fosaprepitant is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while you are being treated with fosaprepitant.

It is not known whether fosaprepitant passes into breast milk or if it could harm a nursing baby. Before you receive this medication, tell your doctor if you are breast-feeding a baby.

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Copyright © 2010 Lexi-Comp, Inc. and/or Cerner Multum, Inc. All rights reserved. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

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