Dalfopristin and quinupristin is a combination antibiotic that fights severe or life-threatening infection caused by bacteria.

Dalfopristin and quinupristin is used to treat severe infections in the blood and other body systems.

Dalfopristin and quinupristin may also be used for other purposes not listed in this medication guide.

You should not receive this medication if you are allergic to dalfopristin and quinupristin.

Before receiving dalfopristin and quinupristin, tell your doctor if you have liver or kidney disease, or a history of any type of allergy.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

You should not receive this medication if you are allergic to dalfopristin and quinupristin.

If you have certain conditions, you may need a dose adjustment or special tests to safely receive this medication. Before you receive dalfopristin and quinupristin, tell your doctor if you are allergic to any drugs, or if you have:

• liver disease;

• kidney disease; or

• a history of any type of allergy.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether dalfopristin and quinupristin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.