Dorzolamide ophthalmic reduces the amount of fluid in the eye, which decreases pressure inside the eye.

Timolol ophthalmic is a beta-blocker that also reduces pressure inside the eye.

The combination of dorzolamide and timolol ophthalmic (for the eyes) is used to treat certain types of glaucoma and other causes of high pressure inside the eye.

Dorzolamide and timolol ophthalmic may also be used for purposes not listed in this medication guide.

Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using dorzolamide and timolol ophthalmic. Do not use the medications at the same time.

Dorzolamide and timolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

You should not use this medication if you are allergic to dorzolamide (Cosopt or Trusopt) or timolol (Blocadren, Betimol, Istalol, Timoptic), or if you have:

• a history of asthma;

• chronic obstructive pulmonary disease (COPD); or

• a serious heart condition such as "AV block," slow heartbeats, heart failure, or if you have recently had a heart attack.

To make sure you can safely use dorzolamide and timolol ophthalmic, tell your doctor if you have any of these other conditions:

• narrow-angle glaucoma;

• breathing problems such as bronchitis or emphysema;

• a history of heart disease or congestive heart failure;

• diabetes;

• a muscle disorder such as myasthenia gravis;

• kidney disease;

• liver disease; or

• a thyroid disorder.

FDA pregnancy category C. It is not known whether dorzolamide and timolol ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether dorzolamide and timolol ophthalmic passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medicine.

Do not use this medicine in a child younger than 2 years old.