Bendroflumethiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Nadolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

The combination of bendroflumethiazide and nadolol is used to treat high blood pressure (hypertension).

Bendroflumethiazide and nadolol may also be used for other purposes not listed in this medication guide.

You should not use this medication if you have asthma, severe or uncontrolled heart failure, a serious heart condition such as "sick sinus syndrome" or "AV block," or if you are unable to urinate.

Before using this medication, tell your doctor if you have congestive heart failure, kidney or liver disease, cirrhosis, bronchospastic lung disease, a thyroid disorder, gout, lupus, diabetes, or if you are allergic to sulfa drugs.

If you are diabetic, check your blood sugar carefully. Using nadolol can make it harder for you to tell when you have low blood sugar. Your insulin or diabetic medication needs may change while you are taking bendroflumethiazide and nadolol. Talk with your doctor before changing any doses.

Avoid drinking alcohol, which can lower your blood pressure and may add to the side effects of bendroflumethiazide and nadolol.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Keep using this medication even if you feel fine. High blood pressure often has no symptoms.

There are many other medicines that can interact with bendroflumethiazide and nadolol. Tell your doctor about all the prescription and over-the-counter medications you use.

You should not use this medication if you are allergic to bendroflumethiazide or nadolol, or if you have:

• asthma;

• severe or uncontrolled heart failure;

• a serious heart condition such as "sick sinus syndrome" or "AV block" (2nd or 3rd degree); or

• if you are unable to urinate.

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before using bendroflumethiazide and nadolol, tell your doctor if you have:

• congestive heart failure;

• kidney disease;

• liver disease (or cirrhosis);

• bronchospastic lung disease;

• a thyroid disorder;

• lupus;

• gout;

• diabetes; or

• if you are allergic to sulfa drugs.

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Bendroflumethiazide and nadolol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.