Bumetanide is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine.

Bumetanide treats fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.

Bumetanide may also be used for other purposes not listed in this medication guide.

You should not use bumetanide if you are allergic to it, if you are unable to urinate, if you have severe kidney or liver disease, or if you are severely dehydrated.

Before you take bumetanide, tell your doctor if you have kidney or liver disease, gout, diabetes, or an allergy to sulfa drugs.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.

Bumetanide will make you urinate more often and you may get dehydrated easily. Follow your doctor's instructions about using potassium supplements or getting enough salt and potassium in your diet.

Avoid becoming dehydrated. Follow your doctor's instructions about the type and amount of liquids you should drink while you are taking bumetanide.

There are many other drugs that can interact with bumetanide (including some over-the-counter medicines). Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

You should not use bumetanide if you are allergic to it, or if you have:

• severe kidney disease or are unable to urinate;

• severe liver disease; or

• if you are severely dehydrated.

If you have any of these other conditions, you may need a dose adjustment or special tests:

• kidney disease;

• liver disease;

• a history of heart rhythm disorder;

• gout;

• diabetes; or

• an allergy to sulfa drugs.

FDA pregnancy category C. It is not known whether bumetanide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether bumetanide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking bumetanide.