The Cycloset brand of bromocriptine is used together with diet and exercise to treat type 2 diabetes. Cycloset is not for treating type 1 diabetes.

The Parlodel brand of bromocriptine is used to treat certain conditions caused by a hormone imbalance in which there is too much prolactin in the blood (hyperprolactinemia). Symptoms include lack of sexual development in adolescents. Women may have missed menstrual periods, loss of interest in sex, hot flashes, infertility, or unexpected breast milk production and leakage from the nipples. Men may have enlarged breasts, decreased libido, decreased facial or body hair, and loss of muscle. Parlodel is also used to treat these disorders when they are caused by brain tumors that can produce prolactin.

Parlodel is sometimes used together with surgery or radiation in treating acromegaly, a condition caused by a pituitary gland tumor that produces too much growth hormone.

Parlodel is also used to treat symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control.

Bromocriptine may also be used for purposes not listed in this medication guide.

You should not use Cycloset if you are breast-feeding, if you have migraine headaches that cause you to faint, or if you are in a state of diabetic ketoacidosis (Call your doctor for treatment with insulin).

You should not use Parlodel if you have uncontrolled high blood pressure, if you have high blood pressure caused by pregnancy (eclampsia or preeclampsia), or if you have recently had a baby and you have a history of coronary artery disease or severe heart disease. You may need to stop taking Parlodel if you become pregnant during treatment. Follow your doctor's instructions.

You should not breast-feed a baby while taking bromocriptine.

Tell your doctor right away if you become pregnant while taking bromocriptine.

You should not use this medication if you are allergic to bromocriptine or to an ergot medicine (Ergomar, Cafergot, Migergot, D.H.E. 45, Migranal, Methergine).

You should not use Cycloset if:

• you are breast-feeding;

• you have migraine headaches that cause you to faint; or

• you are in a state of diabetic ketoacidosis (Call your doctor for treatment with insulin).

You should not use Parlodel if you have:

• uncontrolled high blood pressure (hypertension);

• hypertension caused by pregnancy (including eclampsia and preeclampsia);

• if you are also using an ergot medicine to treat migraine headaches; or

• if you have recently had a baby and you have a history of coronary artery disease or severe heart disease.

Bromocriptine may contain lactose. Before taking this medication, tell your doctor if you have a hereditary form of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.

To make sure you can safely take bromocriptine, tell your doctor if you have any of these other conditions:

• high or low blood pressure, heart disease, or a history of heart attack;

• liver or kidney disease;

• a stomach ulcer or history of stomach or intestinal bleeding; or

• a tumor of the pituitary gland;

• a history of mental illness or psychosis.

FDA pregnancy category B. Bromocriptine is not expected to harm an unborn baby. However, a pituitary tumor in the mother can expand during pregnancy. High blood pressure can also occur during pregnancy and bromocriptine could be dangerous if taken by a pregnant woman with high blood pressure. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Some women take Parlodel in order to normalize menstrual periods and increase their chances of becoming pregnant. Tell your doctor as soon as you become pregnant. You may need to stop taking Parlodel. Follow your doctor's instructions.

If you are not taking Parlodel to help you get pregnant, use a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy during treatment. Your doctor may also want you to have a pregnancy test every 4 weeks during treatment.

Bromocriptine lowers the hormone needed to produce breast milk. Do not breast-feed a baby while taking bromocriptine.