Hydralazine is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.

Hydralazine is used to treat high blood pressure (hypertension).

Hydralazine may also be used for other purposes not listed in this medication guide.

You should not use this medication if you are allergic to hydralazine, or if you have coronary artery disease, or rheumatic heart disease affecting the mitral valve.

Before taking hydralazine, tell your doctor if you have kidney disease, lupus, angina pectoris (chest pain), or if you have ever had a stroke.

While taking hydralazine, avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Call your doctor at once if you have a serious side effect such as fast or pounding heartbeats, swelling, numbness or tingling, dark-colored urine, joint pain or swelling with fever, chest pain, weakness or tired feeling, and urinating less than usual or not at all.

To be sure this medication is helping your condition and is not causing harmful effects, your blood pressure will need to be checked often. You may also need occasional blood tests. Do not miss any scheduled appointments.

Keep using hydralazine as directed, even if you feel well. High blood pressure often has no symptoms, so you may not know when your blood pressure is high. You may need to use blood pressure medication for the rest of your life.

You should not use this medication if you are allergic to hydralazine, or if you have:

• coronary artery disease; or

• rheumatic heart disease affecting the mitral valve.

Before taking hydralazine, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease,

• lupus;

• angina pectoris (chest pain); or

• if you have ever had stroke.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Hydralazine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.