Peptic Ulcer Disease (Cleveland Clinic)

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Who is more likely to get ulcers?
You may be more likely to develop ulcers if you:

  • Are infected with the H. pylori bacterium
  • Take NSAIDs such as aspirin, ibuprofen, naproxen, and many others
  • Have a family history of ulcers
  • Smoke
  • Have another illness, such as liver, kidney, or lung disease
  • Drink alcohol regularly

How are ulcers diagnosed?
Your doctor may be able to make the diagnosis just by talking with you about your symptoms. However, to confirm the diagnosis one of several tests should be taken. First, your doctor may ask you to take an acid-blocking medication for a short period of time to see if your symptoms improve.

If needed, your doctor may recommend a procedure called an upper endoscopy. It involves inserting a small, lighted tube (endoscope) through the throat and into the stomach to look for abnormalities. This procedure is usually given if you are having severe symptoms of ulcers.

Often, doctors will frequently treat without confirming the diagnosis using endoscopy. If the cause is not likely to be from NSAIDs, then it is very likely to be from H. pylori. Most doctors will now test for H. pylori and will treat specifically for that in addition to giving medications to reduce the symptoms.

H. pylori can be detected either directly by taking a sample during the upper endoscopy described above or indirectly with a blood test or a breath test.

Though ulcers often heal on their own, you shouldn't ignore their warning signs. If not properly treated, ulcers can lead to serious health problems.

How are ulcers treated?
There are several ways in which ulcers can be treated, including making changes to ones lifestyle, taking medication, and/or undergoing surgery.

Lifestyle
To treat an ulcer, first eliminate substances that can be causing the ulcers. If you smoke or drink alcohol, stop. If the ulcer is believed to be caused by the use of NSAIDs, they need to be stopped.

Medications

  • Proton pump inhibitors (PPI). Proton pump inhibitors reduce acid and allow the ulcer to heal. PPIs include Prilosec®, Prevacid®, Aciphex®, Protonix®, and Nexium®.
  • Antibiotics. Antibiotics are used to treat H. pylori. There are multiple combinations of antibiotics that are taken for one to two weeks along with a PPI. Some doctors also recommend taking Pepto-Bismol®.
  • Endoscopy. Some bleeding ulcers can be treated through the endoscope.
  • Surgery. An operation may be needed if the ulcer has created a hole in the stomach wall or if there is serious bleeding.

Will drinking milk help cure an ulcer?
No. Milk can make your ulcer worse. Milk provides brief relief of ulcer pain because it coats the stomach lining. But milk also stimulates your stomach to produce more acid and digestive juices, which can aggravate ulcers.

How can I prevent ulcers?

  • If you smoke, quit. People who smoke are twice as likely to develop ulcers. Ulcers also heal more slowly in people who smoke.
  • Avoid overindulging in alcohol.
  • If you have symptoms of an ulcer, contact your doctor.
  • Don't overuse NSAIDs.

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Last Updated: 10/19/2008

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