Statins and Statin Combinations for High Cholesterol

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Statins and Statin Combinations for High Cholesterol

Examples

Statins

Brand NameGeneric Name
Lipitoratorvastatin
Lescol fluvastatin
Altoprev, Mevacorlovastatin
Livalopitavastatin
Pravacholpravastatin
Crestorrosuvastatin
Zocorsimvastatin

Statin combinations

Brand NameGeneric Name
Caduetatorvastatin and amlodipine, a calcium channel blocker for high blood pressure
Advicorlovastatin and niacin (nicotinic acid)
Vytorinsimvastatin and ezetimibe, a cholesterol absorption inhibitor
Simcorsimvastatin and niacin (nicotinic acid)

How It Works

Statins block an enzyme the body needs to produce cholesterol. As a result, LDL ("bad") cholesterol levels in the blood go down, thereby lowering total blood cholesterol levels.

Statins may be taken alone or taken with other cholesterol medicines such as fibric acid derivatives, bile acid sequestrants, or nicotinic acid. Statins may also be combined with other types of medicines into one pill.

Why It Is Used

Statins are used to lower LDL cholesterol. Statins can help lower the risk of heart attack, stroke, and death in people who are at high risk of a heart attack or stroke.

How Well It Works

Statins and statin combinations can:

  • Lower the risk of heart attack.
  • Lower stroke risk.
  • Reduce LDL by 18% to 55%.1 This means that if your LDL is 200, taking a statin could lower your LDL to between 164 and 90.
  • Increase HDL by 5% to 15%.1 This means that if your HDL is 60, taking a statin could increase your HDL to between 63 and 69. The higher your HDL, the better. An HDL of 60 and higher protects against heart disease.
  • Reduce triglycerides by 7% to 30%.1 This means that if your triglycerides are 200, taking a statin could lower your triglycerides to between 186 and 140.

Side Effects

All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.

Here are some important things to think about:

  • Usually the benefits of the medicine are more important than any minor side effects.
  • Side effects may go away after you take the medicine for a while.
  • If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.

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This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.
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