Diuretics for High Blood Pressure

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Diuretics for High Blood Pressure

Examples

Thiazide diuretics

Brand NameGeneric Name
Clorpres, Tenoretic, Thalitonechlorthalidone and chlorthalidone combinations
Capozide, Dyazide, Hyzaar, Lopressor HCT, Maxzide, Prinzidehydrochlorothiazide and hydrochlorothiazide combinations

Loop diuretics

Brand NameGeneric Name
bumetanide 
Lasixfurosemide
Demadextorsemide

Potassium-sparing diuretics

Brand NameGeneric Name
amiloride and amiloride combinations 
Aldactazide, Aldactonespironolactone and spironolactone combinations
Dyazide, Maxzidetriamterene and triamterene combinations

Quinazoline diuretics

Brand NameGeneric Name
Zaroxolynmetolazone

How It Works

Diuretics cause the kidneys to remove more sodium and water from the body, which helps to relax the blood vessel walls, thereby lowering blood pressure.

Diuretics often are combined with other high blood pressure medicines. Some of the brand names listed here are a combination of a diuretic and another medicine. Using both a diuretic and another medicine often works well, because diuretics can enhance the effect of the other medicines and sometimes prevent the fluid retention that can occur.

Potassium-sparing diuretics, unlike most other diuretics, do not cause potassium levels to drop. Rather, they may lead to high potassium levels.

Why It Is Used

Thiazide diuretics are recommended as the first line of treatment for high blood pressure. They are usually recommended as one of at least two medicines to control high blood pressure.

Quinazoline diuretics are similar to the thiazide diuretics, but are used only in certain people such as those with kidney problems and when other diuretics have not worked.

Loop diuretics are prescribed for people who also have heart failure, kidney problems, or swelling in their legs (edema). But they are rarely prescribed for people who have high blood pressure alone.

Potassium-sparing diuretics might be used, along with other diuretics, if you have low potassium levels.1

How Well It Works

Diuretics lower blood pressure.1 By lowering blood pressure, they help lower the risk for heart disease, heart attack, and stroke.

Side Effects

All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.

Here are some important things to think about:

  • Usually the benefits of the medicine are more important than any minor side effects.
  • Side effects may go away after you take the medicine for a while.
  • If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.
By: Healthwise Staff
Medical Review: E. Gregory Thompson, MD - Internal Medicine
Robert A. Kloner, MD, PhD - Cardiology
Last Revised: April 4, 2011

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