Angiotensin II Receptor Blockers (ARBs) for High Blood Pressure

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Angiotensin II Receptor Blockers (ARBs) for High Blood Pressure

Examples

Brand NameGeneric Name
Atacandcandesartan
Teveteneprosartan
Avaproirbesartan
Cozaar, Hyzaarlosartan
Benicarolmesartan
Micardistelmisartan
Diovanvalsartan

How It Works

These medicines block the action of a hormone that causes blood vessels to narrow. As a result, blood vessels may relax and open up. This makes it easier for blood to flow through the vessels, which reduces blood pressure. Also, these drugs increase the release of sodium and water into the urine, which also lowers blood pressure.

Why It Is Used

Angiotensin II receptor blockers (ARBs) may be used alone or combined with other medicine—often a diuretic—to treat high blood pressure.

ARBs may be used by people who cannot take ACE inhibitor medicines. ACE inhibitors can cause an annoying cough. This cough may be hard for some people to live with. So doctors may prescribe an ARB instead. ARBs are less likely to cause a cough.

ARBs are also used by people have heart problems such as coronary artery disease or heart failure. ARBs might be used by people who type 2 diabetes and have early signs of kidney disease or who have kidney disease from diabetes (diabetic nephropathy).

How Well It Works

Angiotensin II receptor blockers (ARBs) reduce blood pressure as effectively as angiotensin-converting enzyme (ACE) inhibitors but are less likely to cause the cough that is associated with ACE inhibitors.

If you are taking an ARB because you have diabetes and early signs of kidney problems, or have kidney disease, these medicines can slow or prevent further damage to your kidneys.1

Side Effects

All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.

Here are some important things to think about:

  • Usually the benefits of the medicine are more important than any minor side effects.
  • Side effects may go away after you take the medicine for a while.
  • If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.

Call 911 or other emergency services right away if you have:

By: Healthwise Staff
Medical Review: E. Gregory Thompson, MD - Internal Medicine
Robert A. Kloner, MD, PhD - Cardiology
Last Revised: April 4, 2011

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