Over-the-Counter: Choosing the Right Allergy Medications

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Allergy sufferers looking for relief at the local pharmacy are faced with many product choices. To make the right choice for you, you first need to recognize and understand your symptoms. Then, learn what medicines are available over-the-counter, how each medicine works, and which symptoms each type of medicine is designed to treat.

What's happening: The allergic response
Allergies are the immune system's response to normally harmless substances that it mistakes for harmful substances. Exposure to what is normally a harmless substance, such as pollen, causes the immune system to react as if the substance is harmful. Substances that cause allergies are called allergens.

When you come into contact with an allergen, your immune system kicks into gear. If you are allergic to pollens or other substance that you breathe in, the membranes in your nose might become irritated, swollen, and inflamed, leading to symptoms such as sneezing, a runny nose, headache, and/or congestion (pressure) in your nose and head. Your eyes also might water and itch. If you are allergic to something that comes into contact with your skin, you might break out in hives or a rash. Taking the right medicine for your symptoms is important.

Medicines available over-the-counter to treat allergy symptoms
There are many medicines available over-the-counter to treat mild allergy symptoms. The most common medicines are antihistamines and decongestants. Some medicines combine an antihistamine and a decongestant, and some include a pain reliever.

Antihistamines - When you inhale an allergen, special cells in your nose and sinuses (the open spaces behind your nose and eyes) release a chemical called histamine. Histamine causes the tissues in your nose to itch and swell, and to alter the mucus it secretes. (It becomes clear and runny.) Antihistamine medicines block histamine from interacting with the nasal tissues, thus preventing symptoms.

Decongestants - In response to an allergen, the tissues in your nose swell, and increase their production of fluid and mucus. As a result, you might feel fullness or pressure in your nose and head (congestion), and you might have trouble breathing through your nose. Decongestants help reduce the swelling, which relieves the feeling of pressure and improves airflow through your nose.

Topical corticosteroids - Many products, especially those containing fragrances and/or dyes, can irritate the skin or cause an allergic reaction. Symptoms include itchy, scaly red patches or rash; swelling; hives; or blisters. Topical (on the skin) corticosteroids can help control the itching, swelling, and redness.

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Last Updated: 1/26/2007

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