Antihistamines for Allergic Rhinitis

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Antihistamines for Allergic Rhinitis

Examples

Older (first-generation) over-the-counter and prescription antihistamines

Brand NameGeneric Name
Semprex-Dacrivastine
brompheniramine maleate 
Chlor-Trimetonchlorpheniramine maleate
Tavist-1clemastine fumarate
Benadryldiphenhydramine
Vistarilhydroxyzine
promethazine  

Newer (second-generation) over-the-counter antihistamines

Brand NameGeneric Name
Zyrteccetirizine
Alavert, Claritinloratadine

Newer (second-generation) prescription antihistamines

Brand NameGeneric Name
Astelinazelastine
Clarinexdesloratadine
Allegrafexofenadine
Xyzallevocetirizine
Patanaseolopatadine

Antihistamines may be available as tablets, capsules, nasal sprays, or liquids. You can use them alone or combined with decongestants to treat allergic rhinitis.

How It Works

Many symptoms of allergic rhinitis, such as sneezing, itching, and runny nose, occur when your body releases a chemical called histamine. Antihistamine medicines block histamine and may reduce your symptoms.

Why It Is Used

You can use antihistamines to stop or reduce sneezing, runny nose, and watery and itchy eyes caused by an allergic reaction.

How Well It Works

All of these antihistamines work equally well to relieve sneezing, itching, and runny nose.

  • Antihistamines begin to provide relief in 30 minutes to 2 hours.
  • Antihistamines dry up the runny nose caused by allergies, but they usually do not clear up stuffiness.

Side Effects

All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.

Here are some important things to think about:

  • Usually the benefits of the medicine are more important than any minor side effects.
  • Side effects may go away after you take the medicine for a while.
  • If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.

Call 911 or other emergency services right away if you have:

  • Trouble breathing.
  • Hives.
  • Swelling of your face, lips, tongue, or throat.

Call your doctor if you have:

  • Fast or irregular heartbeat.
  • Fever.
  • Unusual bleeding or bruising.
  • Belly pain.
  • Unusual tiredness or weakness.

Common side effects of this medicine include:

  • Drowsiness.
  • Dry mouth, nose, or throat.
  • Stomach upset.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

Illustrations

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    By: Healthwise Staff
    Medical Review: E. Gregory Thompson, MD - Internal Medicine
    Rohit K Katial, MD - Allergy and Immunology
    Last Revised: June 30, 2011

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    This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.
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